Hair loss biology in women: So what causes androgenetic alopecia / pattern hair loss anyway? The biology of female pattern hair loss is similar to that seen with male pattern baldness, although there are a few differences due to the different levels of hormone production and differences in expression of some of the enzymes that regulate the conversion of androgens.
While hair loss can be a depressing issue, many men have essentially accepted it as an inevitable part of growing up. But hair loss in womens can be extremely traumatic. Unfortunately, society places an immense amount of pressure on women to constantly uphold a flawless level of health and beauty,
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Androgenetic alopecia has been associated with several other medical conditions including coronary heart disease, enlargement of the prostate in men and an increased risk of polycystic ovary syndrome (PCOS) in women. Coronary artery disease For a long time there has been an indication that bald men have a higher risk
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All steroid hormones act by diffusing through the plasma membrane into the target cell and binding to specific intracellular receptors. Similarly, androgens, like other steroids, diffuse across plasma membranes and combine with a cytosolic or nuclear receptor protein. The cytosol is the internal fluid of the cell where a large
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Research studies in patients with androgen insensitivity syndromes and 5alpha – reductase type-2 deficiencies indicate that androgenetic alopecia is induced by activation of follicular androgen receptors by dihydrotestosterone (DHT), a potent stimulator of hair loss in the scalp. Although the level of DHT may be directly dependent on the activity
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So far, the predisposing genes for androgenetic alopecia are unknown and the paradoxical relation between the molecular steps involved in androgen-dependent beard growth and androgen-dependent scalp hair loss is still unclear. However, androgenetic alopecia can be defined as a dihydrotestosterone (DHT) – dependent process with continuous miniaturization (conversion of terminal
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